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Additionally, a randomized, double-blind, placebo-controlled trial in 162 elderly people (70 years) with mild vitamin B 12 deficiency found that vitamin B 12 supplementation for 24 weeks, alone or in combination with folic acid, did not improve memory performance (117)
One mouse study found no change in mean lifespan
Whilst injections bypass gut absorption, conditions like active Crohn's disease or coeliac disease may cause increased metabolic demands that could influence how quickly B12 is utilised
Yong, T
5C), and induced L2HGDH expression (Fig
Link to the PDF with some thoughts below: fda.gov/media/193343/d The FDA reviewed 5 reports with 109 humans: 24 healthy volunteers rectal 53-person Ulcerative Colitis trial rectal 17 knee-pain patients intra-articular 12 bladder-pain patients intravesical 2 healthy volunteers IVThe FDA has 4 broad reasons against BPC: 1
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