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In particular, the activity of BAM3, which is primarily involved in night starch degradation in mesophyll cells, is decreased by cold stress [266,267]

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Research shows that both moderate-intensity continuous training (MICT, 50%70% VO 2 max) and high-intensity interval training (HIIT, 85%95% VO 2 max) can effectively activate the Nrf2 pathway, with HIIT being 30%40% more effective in upregulating antioxidant enzymes than MICT (Martinez-Canton et al., 2024)

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Epigallocatechin gallate (EGCG), a bioactive compound derived from green tea (Eng et al., 2018), has been demonstrated to inhibit the formation of D-2-hydroxyglutarate (D-2-HG) from glutamate, augmenting the radiosensitivity in IDH mutant cancers (Peeters et al., 2019)

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