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However, cell death also has a strong proinflammatory effect, which can worsen the damage to renal tubules through feedback regulation, and persistent inflammation and damage eventually result in renal tubulointerstitial fibrosis[146]

Nominally, these Japanese subjects also appeared to exhibit a shorter mean T 1/2 and a higher mean CLR than that observed in the Caucasian subjects

What do randomized controlled trials of high-dose daily vitamin B12 supplementation show about the effects on cancer risk, death, and longevity

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