ghk-cu plasma levels decline with age Copper Peptide Powder – 99.7%+ Pure Cosmetic-Grade Ingredient for DIY Serums, Creams & Scalp Tonics GHK-Cu: Everything You Need To

The peptide forms a stable complex with copper ions, and this GHK-copper combination triggers gene expression changes affecting tissue regeneration , inflammation, and collagen synthesis

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This suggests that GHK likely exists predominantly as GHK-Cu under normal physiological conditions (Pickart, 2008)

Passeron T, Kerob D, Le Dantec G, et al

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Sarbaziha notes that levels peak in young adulthood before declining, and she outlines how the compound modulates gene expression tied to repair processes in addition to exerting acute effects on oxidative stress