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A novel function of the human CLS1 in phosphatidylglycerol synthesis and remodeling
GST tagged fusion proteins bind to glutathione agarose (column 2) and after washing, are eluted with elution buffer with excess glutathione (column 3)
The tumor tissue of osteosarcoma was obtained, cut into small fragment, and transplanted subcutaneously into BALB/c nude mice
Low GSH in aging is associated with lower intake of GSH precursors, mainly cysteine, and lower GSH synthesis evidencing diminished function of nuclear factor erythroid 2related factor 2 (Nrf2)-dependent inductive mechanisms that enhance glutamate cysteine ligase expression, rate limiting factor for the synthesis of GSH (McCarty and DiNicolantonio, 2015)
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