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Stage one: the inflammatory phase The moment a bone fractures, blood vessels within the bone and surrounding periosteum rupture

If the pain is refractory to those treatments, the use of intravenous ketamine in infusion has recently been described as an option.117119 In addition, enabling the patient to rest in a quiet and darkened environment and maintaining good hydration with crystalloid solutions, even when the patient shows no signs of dehydration, appear to be beneficial

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Li B,Huang h,hou J

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Yang J, Dai X, Xu H, Tang Q, Bi F