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Glutathione is composed of three amino acids (L-glutamic acid, L-cysteine and glycine) and can be found in every cell

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Both IDH1 and IDH2 enzymes utilize NADP + as their cofactor and generate NADPH via oxidative decarboxylation of isocitrate outside the context of the TCA cycle

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Taken together, our in vitro, in vivo and ex vivo models provide compelling evidence regarding the therapeutic effect and safety profile of TLR2 pep-orid-liposome as a promising clinical treatment for AML