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Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials

Jarvis JN, Lawrence DS, Meya DB, Kagimu E, Kasibante J, Mpoza E, Rutakingirwa MK, Ssebambulidde K, Tugume L, Rhein J, Boulware DR, Mwandumba HC, Moyo M, Mzinganjira H, Kanyama C, Hosseinipour MC, Chawinga C, Meintjes G, Schutz C, Harrison TS (2022) Single-dose liposomal amphotericin B treatment for cryptococcal meningitis

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The cytotoxicity and clearance of mutant huntingtin and other misfolded proteins

The dual role of ROS as signaling molecules and potential toxins emphasizes their importance in maintaining oxygen homeostasis and their involvement in disease pathogenesis when dysregulated [545]

Those studies indicate that short-term exposure to elevated N-Me-2PY levels may exert protective effects, whereas prolonged exposure is probably harmful due to the importance of DNA repair [105]