Thomsen et al., 1992
It is more common for results to be low, although pituitary tumors (sometimes leading to gigantism or acromegaly) can produce unusual results

Abbreviations RA: Rheumatoid arthritis TCM: Traditional Chinese medicine BR: Bilirubin RM: Red blood cell membranes Cel: Celastrol ROS: Reactive oxygen species RES: Reticuloendothelial system HA: Hyaluronic acid PBS: Phosphate Buffered Saline MD: Molecular dynamics RMSD: Root mean square deviation SASA: Solvent-accessible surface area 1 H-NMR: Hydrogen nuclear magnetic resonance spectroscopy DMSO-d6: Dimethyl sulfoxide-d6 D 2 O: Deuterium oxide Cou6: Coumarin 6 DIR: 1,1-Dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodine DCFH-DA: 2,7-dichlorofluorescein diacetate DAF-FM DA: 4-amino-5-methylamino-2,7-difluorofluorescein diacetate NO: Nitric oxide WB: Western blotting PCA: Principal component analysis DEGs: Differentially expressed genes KEGG: Kyoto Encyclopedia of Genes and Genomes micro-CT: Micro-computed tomography H&E: Hematoxylin and eosin SO-FG: Senna O-Fixed Green TRAP staining: Tartaric acid staining PBS: Phosphate-buffered saline ALP staining: Alkaline phosphatase staining ALT: Aminotransferase AST: Aspartate aminotransferase CCK8: Cell Counting Kit-8 UV-vis: Ultraviolet-Visible Spectrophotometryp FT-IR: Fourier Transform Infrared Spectroscopy LPS: Lipopolysaccharide SDS-PAGE: Sodium dodecyl sulfate-polyacrylamide gel electrophoresis References Smolen JS, Aletaha D, Barton A, Burmester GR, Emery P, Firestein GS, et al

Int J Mol Sci 25(20)
[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Black L.J., Allen K.L., Jacoby P., Trapp G.S., Gallagher C.M., Byrne S.M., Oddy W.H
It should not be combined casually with other strong actives without guidance