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Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects

A loss-of-function mutation in the GSTM1 gene, encoding one of three isoforms of glutathione-S-transferase (GST), an antioxidant enzyme, was linked to NA-AION [543,544]

Participants were instructed to continue taking the capsules for six months, maintain a daily pill diary, and return all unused capsules at each visit

The ketogenic diet attenuates both hyperactivity in mTOR pathway and astrogliosis through regulation of AMPK signaling in the epileptic brain

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