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Additional information about the model development is available in the Supplementary Material

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The molecular structure explains why this step is rate-limiting: the steric bulk of the branched alcohol and the hydrophobicity of the diester slow water access to the ester carbonyl, and the reaction is enzyme-catalysed rather than spontaneous

In the gut specifically, KPV is absorbed through a dedicated intestinal transporter (PepT1), allowing it to calm inflammation directly inside epithelial cells

In research settings, Glow is often explored as part of peptide stacking investigations and peptide combination studies

Expression, purification, and cytotoxic evaluation of IL24-BR2 fusion protein