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What they found: Mean weight loss: 2.6 kg vs 2.3 kg placebo , a difference of only 0.3 kg (1 %) Statistically non-significant Clinically unsatisfactory for the obesity indication Safety profile remained favorable Why it matters: The study stopped the development of AOD-9604 as a drug

However, it's important to recognize that while a B12 deficiency may contribute to depression in some cases, it is not the sole cause

Systemic distribution via abdominal fat pad injection also delivers BPC-157 throughout the body and is effective for general or gut protocols

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Currently, secukinumab and ixekizumab are two FDA-approved IL-17a antagonists for psoriatic arthritis treatment [72,73]

Together, they suggest that BPC-157 affects blood vessel growth, inflammation, and tissue repair in animal models, while TB-500 appears to help cells move, heal, and rebuild