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Mechanistically, GAS5 inhibits proliferation and promotes apoptosis through the regulation of E2F1, p21, and p53, and suppresses oncogenic pathways including EGFR, MAPK, and AKT

The overall direction of these changes moves gene expression patterns from states associated with disease and aging toward healthier profiles

But heres the inconvenient truth that the peptide salesmen wont mention: the history of medicine is littered with compounds that worked brilliantly in rodents and failed spectacularly in humans

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