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Loop diuretics used in the treatment of CHF, notably furosemide, increase thiamin excretion, potentially leading to thiamin deficiency (76, 77)

If levels of oxalate in the glomerular filtrate increase (hyperoxaluria) it can chelate Ca 2+ ions forming the insoluble compound, calcium oxalate

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173 Arginine in cancer Citrulline and aspartate can be converted to arginine in normal cells by arginine-succinate synthetase 1 (ASS1) and arginine-succinate lyase (ASL) in the urea cycle

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But does this mean that B12 shots, in which a nurse injects a vile of B12 into your hip or buttocks, is a good solution to this growing problem