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Viral entry is demonstrated to require the activity of the cysteine proteases cathepsin B and cathepsin L (CatB/L) as well as the serine protease TMPRSS2 for S protein priming

The compound profile is still evolving, and new data regularly updates the understanding of optimal dosing, safety parameters, and combination possibilities

10.1152/physrev.00032.2022 153 ThabetE.YusufA.AbdelmonsifD

Curr Opin Toxicol 4:1621

Injecting any substance into the body carries inherent risks, including the potential for allergic reactions, infections, and other adverse effects

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