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[41] : 975 Children diagnosed with low serum B 12 can be treated with intramuscular injections, then transitioned to an oral dietary supplement

When the NNMT enzyme is overactive, its often associated with insulin resistance, a condition where your cells dont respond well to insulin and cant easily take up glucose from your blood

Patients with pernicious anemia or others who cannot absorb B from food typically need lifelong B therapy, often on a monthly injection schedule

Dietary and oral supplementation are the most common ways of achieving adequate B12 levels, but this can be challenging for certain individuals depending on their diet, intestinal health, ability to convert to active forms and other health conditions

The frequency of B12 injections varies, but typically ranges from weekly to monthly

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