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Set clear expectations : Establish family rules about not using commercial tobacco products

Some clinical trials only include patients who have not yet received treatment

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This classic approach has been commonly applied 35,36,37,38,39 and has key advantages 26 , including that it is relatively fast to apply and is more interpretable compared to more sophisticated methods, such as Bayesian regression models that perform shrinkage 39,40,41

The risk continuum is one way of communicating the differences in risk when using different kinds of nicotine-containing products

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