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On one side, this signaling axis could explain the beneficial effects mediated by exercise and caloric restriction in young mice and, on the other side, it could represent a target for determining the adaptive response of skeletal muscle under aging or pathological conditions

The expression of 8-OHdG was increased in 5-FU group as compared to the Control group which might represent DNA damaging effect of 5-FU (Fig

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Liquid-State Kinetics Study Analysis of the kinetics data indicated the first order reaction in almost all tested formulations