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The biphasic response suggests possible mechanisms: lower doses (nanogram range) might work through growth factor upregulation and signaling cascade amplification, while higher doses (microgram range) might involve direct receptor activation or substrate provision for cellular repair

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Mucins, which range in size from 200 kDa to 200 MDa, form an important fraction of the airway mucus layer and have a key role in barrier function 5

A novel adult case of juvenile-onset Alexander disease: complete remission of neurological symptoms for over 12 years, despite insidiously progressive cervicomedullary atrophy

Its thiol group (SH) on the cysteine residue is the primary reactive site, forming glutathione disulphide (GSSG) upon oxidation