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Its illegal in the U.S

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The FDA must also use its Congressionally-mandated authority to address synthetic nicotine as part of this process so that leading disposable brands can no longer slip through this loophole

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Based on pH and protonated versus unprotonated nicotine considerations, JUUL e-cigarettes potentially would lead to more detrimental effects on the lung, while conventional e-cigarettes such as Blu would lead to more systemic effects, such as on cardiovascular and nervous systems