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Together, our data suggest that sustained systemic inflammation and persistent localized BBB dysfunction is a key feature of long COVID-associated brain fog
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All animals (up to 5 mice per cage) were housed under controlled conditions in ventilated cages, including a 12-h light/dark cycle, temperatures of 22 4 C or 21 2 C, and relative humidity ranges of 50 15% or 3070% at The Jackson Laboratory and Oslo University Hospital Rikshospitalet, respectively
Rare variants analysis of neurexin-1 in autism reveals a novel start codon mutation affecting protein levels at synapses
In contrast, M-CuP showed negligible binding to either target, with maximal responses below 5 response units (RU) across all tested concentrations, confirming the essential role of multivalent architecture in cooperative target engagement