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FDX1, a target of the copper ionophore elesclomol, reduces Cu 2 to its more toxic form, Cu, and regulates protein lipoylation through interaction with lipoic acid synthetase (LIAS), which catalyzes the final step of lipoic acid biosynthesis (Figure 2) (Tsvetkov et al., 2022

In some embodiments, otic administration of the formulations or compositions described herein avoids toxicity associated with systemic administration (e.g., hepatotoxicity, cardiotoxicity, gastrointestinal side effects, and renal toxicity) of the active agents

This is done by donating an electron to a free radical, thereby stabilising it and preventing it from causing further damage

"[Anti-arrhythmic effect of phytoadaptogens]." Eksp Klin Farmakol 63 (2000): 29-31

Moist and mold exposure is associated with high prevalence of neurological symptoms and MCS in a Finnish hospital workers cohort

The repair-category comparison should remain catalog-field based