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Nicotine Tolerance: Experienced vapers or former heavy smokers might require more puffs to satisfy their nicotine cravings, potentially increasing the Flum Vape-to-cigarette equivalence

Reynolds launched the products in question shortly after California voters endorsed a statewide ban on menthol cigarettes

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In response to falling nicotine levels, the primitive limbic mind has been somehow pre-programmed to intensify "desire" in order to cause us to ingest new nicotine and thereby avoid any discomfort

[DOI] [PMC free article] [PubMed] [Google Scholar] 61.Whitsett J.A