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Furthermore, multiple studies have provided evidence for dose-dependent exposure effects on gray matter integrity within the insula [18, 85] and vmPFC [19, 22, 86] as well as within the lateral PFC [14, 20] and cerebellum [23]

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Most reported adverse events are mild, but it is important to consider them when evaluating the overall safety profile

Its classification as a Schedule 1 drug means that the federal government determined that cannabis has no currently accepted medical use and has a high potential for abuse

In a recent special communication in BMJ Tobacco Control , we report an alternative explanation for the San Francisco findings