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A study reported that glutathione was most effective when given to people with fatty liver disease intravenously, in high doses

Kidney Int 46:201207 Vijayan A, Franklin SC, Behrend T, Hammerman MR, Miller SB (1999) Insulin-like growth factor I improves renal function in patients with end-stage chronic renal failure

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The production of ROS has the potential to trigger immune cell activation and persistent inflammation