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With technological advancements, it is possible to design nanoparticles to be able to traverse the blood-brain barrier, increase cellular absorption, and give protection against enzymatic degradation, all of which make them an attractive candidate for delivering siRNA to the brain

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USA 108 , 29692974 (2011)

This statement, published in the peer-reviewed Journal of Endocrinology and Metabolism, represents the consensus finding across all six trials and nearly 900 participants

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The enzyme tyrosinase, usually present in an inactive form, is formed in these melanocytes