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This observation means that xCT blockage induces the accumulation of glutamate that is converted into -ketoglutarate instead of being used in glutamate-cysteine exchange and consequently that is why cysteine does not enter the cell and give rise to glutathione

The potential of creatine supplementation for the reduction of Hcy levels and consequently of cell toxicity that is demonstrated in the present study may also be an indirect form of the antioxidant action of this substance

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Without this process, these substances would accumulate in tissues

Biochemistry 36 , 31993206 (1997)

Information Collection Burden for the Proposed Screen Positive Rate for Social Drivers of Health Measure Beginning With the FY 2026 Program Year In section IX.D.5