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Combined use should always follow clinical assessment and should not replace investigation of underlying causes

They may recommend adjusting the dosage, exploring different forms of B12 supplementation, or addressing underlying health issues that could be contributing to your symptoms

It is generally recommended to start low and see how your body reacts before increasing

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The injected hydroxocobalamin is transported via the bloodstream to tissues throughout the body, where it acts as a cofactor for two critical enzymatic reactions: the conversion of homocysteine to methionine and the conversion of methylmalonyl-CoA to succinyl-CoA