10.1093/glycob/cwj115 Glycobiology 209 ZhangJ.De KoninckY
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The authors acknowledge the support of the Open Access Publication Fund of the University of Duisburg-Essen
doi:10.1016/j.jaci.2020.01.017
The non-coenzyme action involves participation of thiamine and/or derivatives, including thiamine triphosphate, in the regulation of ACh synaptic function, consistent with the early data on thiamine as a co-mediator of ACh in neuromuscular synapses, and in allosteric action on metabolic enzymes
Future directions emphasize standardized extraction, AI-driven formulation design, biomarker-based patient stratification, and sustainable production methods