FTH neuron-specific knockout (FTH-KO) mice are more susceptible to ferroptosis after TBI, and the absence of FTH offsets the protective effect of melatonin on ferroptosis induced by TBI, 659 suggesting that melatonin plays a protective role at least in part by inhibiting FTH-mediated ferroptosis in neurons after TBI
Alcohol-induced neuroinflammatory response and mitochondrial dysfunction on aging and Alzheimer's disease
As well, lithium has direct and indirect inhibitory effects on the expression and activity of GSK3 a negative regulator of autophagy (Motoi et al
Curr Drug Targets 7(6):661668 Park MH, Hong JT (2016) Roles of NF-B in cancer and inflammatory diseases and their therapeutic approaches
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doi.org/10.1210/jc.2005-1536 Mayo, K