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Exemplifying this potential, nipocalimab has been shown to potently reduce the level of pre-existing neutralizing Abs against adeno-associated virus vectors in NHPs with moderate Ab titers, which improved vector transduction efficacy to target tissues to close to that observed in Ab-negative nave control animals [360]

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These findings are worth noting they are part of why researchers remain interested in the compound

He is the editorial director of Perio-Implant Advisory and serves on the editorial advisory board of Dental Economics

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