Use of rosuvastatin for this indication is based on one 12-week controlled trial with a 40-week open-label extension period in 176 pediatric patients 10 years of age and older with HeFH and one 2-year open-label, uncontrolled trial in 175 pediatric patients 8 years of age and older with HeFH [see Clinical Studies (14)]
Reported side effects include skin rashes, abdominal pain (in rare instances), and temporary lightning in patches, which normalizes during treatment
Information specific to people with Down syndrome is included below
To this date, the only medically recognized use of NAC in increasing cellular glutathione is in acetaminophen poisoning
A single high-purity batch is meaningful

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