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Age: absorption naturally slows as we get older, so timing can shift over the years

Age-related changes post-40 stem from diminished cellular resilience and repair.[3][11] This resilience is tied to the body's ability to handle oxidative stress and maintain homeostasis, processes that falter as NAD+ levels wane

If left untreated, it can cause irreversible damage to the brain, spinal cord, heart, and other organs

And it's the main reason why foot injuries that would heal quickly in a muscle can drag on for months or years in a tendon

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This is done so Medicare can verify medical necessity