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However, as detailed above, cells that exhibit higher levels of mitochondrial activity are less sensitive to 5FU treatment, and those with compromised mitochondrial function are more sensitive, correlating with intrinsic resistance
Pleurotus pulmonarius laccase can transform 23% of AFB1 but the addition of 1 mM redox mediators, 2,2-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid, or acetosyringone resulted in an increased transformation of AFB1 to about 45% (Loi et al., 2016)
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Drugs Context 11:114 Niazi S, Gheisari M, Moravvej H, Doroodgar F, Niazi F (2022) Efficacy of cysteamine and methimazole in treating melasma: a comparative narrative review