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This temporal representation highlights critical windows for therapeutic intervention, emphasizing the importance of early detection and treatment to mitigate irreversible damage

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Abstract Chronic kidney disease (CKD), characterized by structural, functional, and metabolic derangements, remains a leading cause of end-stage renal disease (ESRD) with profound global health burdens

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There are three: Transport #1: Folate Receptor Alpha (FR) The Primary Route (75-85%) This is the main highway