Use of rosuvastatin for this indication is based on one 12-week controlled trial with a 40-week open-label extension period in 176 pediatric patients 10 years of age and older with HeFH and one 2-year open-label, uncontrolled trial in 175 pediatric patients 8 years of age and older with HeFH [see Clinical Studies (14)]
Deng PB, Hu CP, Xiong Z, Yang HP, Li YY
Use a peptide calculator online if you're unsure, but always understand the basic formula yourself: (Total mg of peptide) / (mL of diluent added) = Concentration in mg/mL
a,b , Representation of the stationary points calculated with ONIOM(B97X-D/6-311 + G(2d,p):ff14SB,gaff2,TIP3P) G(d):ff14SB,gaff2,TIP3P) for the Pt GSTF8-catalysed deprotonation-protonation reaction: flavan-3-on-4-ol ( 7 ), transition state for deprotonation ( 7-TS ), deprotonation product ( 8-enolate ) and cyanidin ( 8-B4 ) bound to the wild-type enzyme ( a ) and the C13S variant ( b )
Very important to differentiate between biotoxin illness and chemical toxicity
Other authors include Bujie Du PhD19, a postdoctoral associate at the Massachusetts Institute of Technology