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Notably, lactate accumulation reprograms macrophage bioenergetic pathways and drives their functional repolarization from pro-inflammatory to reparative phenotypes through shifts in intracellular metabolite availability (67)

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Cellular Processes: Some preclinical studies have examined biological mechanisms in laboratory and animal research settings

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Oral N-Acetyl-Cysteine Attenuates Loss of Dopaminergic Terminals in -Synuclein Overexpressing Mice