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What they found: In normal obese mice: AOD-9604 reduced body fat by 21 % vs placebo, hGH by 24 % The AOD-9604 effect was fully dependent on the 3-adrenergic receptor , in knock-out mice no effect The hGH effect was partly independent of 3-AR , in knock-out mice there was still ~10 % fat reduction AOD-9604 did not raise IGF-1 (control level), whereas hGH raised IGF-1 by 80 % No changes in growth, organ weights (except adipose tissue), fasting insulin Why it matters: The study provided the mechanistic basis for AOD-9604 and confirmed the key business hypothesis: it is possible to separate the lipolytic effect of GH from its growth effect

[21] Pseudovitamins and antivitamins [edit] Pseudovitamin B 12 refers to compounds that are corrinoids with a structure similar to the vitamin, but without vitamin activity

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Adverse Event Reporting : Report any adverse effects to your healthcare provider and to the FDA MedWatch program (www.fda.gov/medwatch or 1-800-FDA-1088)

BloomMD offers a 5-week B12/MIC weight management program designed to support energy, metabolism, and fat loss