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doi: 10.1038/s41589-019-0462-8

Nrf2, a pivotal transcription factor, plays a critical role in the regulation of oxidative stress

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The higher temperatures and greater sunlight exposure may have resulted in excess ROS production at the beginning of the study period in September, then decreased over time with the temperature and sunlight declines in October and November

Artesunate induces ferroptosis in osteosarcoma through ncoa4-mediated ferritinophagy