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Regulatory status (US) Not FDA-approved Category 2 (2023) PCAC July 2026 Compound Melatonin What it is Hormone supplement Mechanism (in plain English) Shifts sleep timing via the circadian system

They are not approved by the FDA to diagnose, treat, cure, or prevent any disease

Clean site with an alcohol swab and let dry

GLP-1 combination therapy Researched alongside GLP-1 agonists like semaglutide (CagriSema) in investigational obesity trials, still under study

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Sub-spec marketplace product that started at 0.7% benzyl alcohol instead of 0.9%, or with pH outside the 4.5-7.0 range, doesn't get the full 28-day window even with perfect storage