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These fragmented mitochondria increase cellular sensitivity to apoptotic stimuli, while enhanced mitochondrial fusion significantly reduces the occurrence of MOMP, thereby inhibiting cell apoptosis [108]

Notably, this study also revealed a positive correlation between telomere length and mtDNA copy number

Nature (2017) 546:3816

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Since mutating the second cysteine of the active site CGYC motif does not affect its dethiolation activity, Mrx1 likely uses a monothiol mechanism for the reduction of S -mycothiolated proteins [49,197]

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