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Reductive stress and mitochondrial dysfunction: the hidden link in chronic disease

doi: 10.1038/ni.3439 112 NakajimaHKunimotoH

But what truly surprised me was how she went beyond just the treatment

Peroxisome proliferator-activated receptor coactivator 1 (PGC-1), a nuclear transcription coactivator, plays several roles in energy metabolism, including involvement in adaptive thermogenesis, mitochondrial biogenesis, hepatic gluconeogenesis, and -oxidation of fatty acids 19,20,21,22

The 3-O-acetylated derivatives showed 100-fold higher IC 50 values relative to the parent mycotoxins when administered to rabbit reticulocytes (Kimura et al., 1998)

Moreover, as previously stated, kidney growth is under IGF-I control