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Airway resistance and subsequently FEV1 reduction can lead to reduced distribution of the drug (Guo et al

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A study was considered to have a high risk of bias if it received at least one negative answer, while a study was classified as low risk of bias only if all questions received positive answers

Toxic signs, which begin within an hour of nicotine ingestion, include vomiting, diarrhea, constricted pupils, drooling, agitation and weakness

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