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We previously showed the presence of mitochondrial dysfunction as early as P15 in the motor cortex, but more precisely in the CSMN of TDP-43 A315T mice 17 , one of the best characterized mouse models of TDP-43 pathology 16,19,33,34

Available at: Bancroft, J., & Janssen, E

Early human trials identified effective daily doses in the range of 12 mg for tanning, with conservative protocols starting lower to minimize side effects such as nausea and flushing [2] [3]

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