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Glutathione redox and autism spectrum disorders Glutathione (L--glutamyl-L-cysteinyl-glycine) is an intracellular peptide that has a wide range of functions including detoxification of xenobiotics and/or their metabolites [21, 22], maintenance of the intracellular redox balance [23], and is the major endogenous antioxidant produced to combat free radical insults [2426]

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Excessive activity causes depletion, particularly in the presence of low cofactors and amino acids