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Ethics statement The study was approved by the Medical Ethical Committee of the San Gallicano Dermatological Institute and it was conducted according to the Declaration of Helsinki principles

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10.1016/j.colsurfb.2016.08.052 Colloids Surf

We thank the Biological Services Unit at QUB for supporting the animal studies undertaken

Its creamy, luxurious texture ensures gentle cleansing without stripping the skins natural moisture, leaving it soft, smooth, and hydrated

There are approximately 14,000 mushroom species, with an estimated 3,000 considered suitable for consumption, and about 270 of these possess the potential to offer therapeutic benefits and enhance human health ( Lentinula edodes , commonly known as shiitake, ranks among the most widely cultivated edible mushrooms globally ( Lentinula edodes lacks a protective cuticle layer on its skin, rendering it susceptible to both physical and microbial damage