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doi: 10.1016/j.fertnstert.2015.05.014

5-Fluorouracil resistance mechanisms in colorectal cancer: from classical pathways to promising processes

Cell transfection and luciferase reporter assay Cells were seeded to reach 7080% of confluency on the day of transfection in a 6-well culture plate

The mobile phases consisted of 0.1% formic acid in water (solvent A) and acetonitrile (solvent B)

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Endoplasmic reticulum (ER) stress and renal dysfunction Arsenic causes ER stress by promoting the accumulation of misfolded proteins, thereby triggering the unfolded protein response aimed at restoring ER function [44, 45]