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In conclusion, our findings support the use of small-molecule-based therapies targeting the erucamideTMEM19 pathway as a promising therapy for the treatment of retinal degenerative diseases, offering potential advantages in terms of efficacy and clinical applicability

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Patients should also be aware that folate supplementation should not be started before B12 deficiency has been treated, as doing so can precipitate or worsen neurological complications

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Review of the indications, methods, and clinical utility of anorectal manometry and the rectal balloon expulsion test