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For the L2 participants, the adjusted frequency for a positive MINI classification for individuals who never smoked was 11.6% (CI [9.9%,13.5%]), 15.9% for those who formerly smoked (CI [14.0%,18.4%]), and 19.8% for those who currently smoked (CI [17.2%,22.8%])

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All of the aforementioned have profound implications for how e-cigarettes should be evaluated, especially when considering that end users are ultimately exposed to the e-cigarette vapor rather than the liquid

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