J Clin Invest 2015;125:1591-602
MettanandaSFisherCAHayDBadatMQuekLClarkKet alEditing an alpha-globin enhancer in primary human hematopoietic stem cells as a treatment for Beta-thalassemia
The Phase 1 single round of DMSA led to a dramatic normalization of RBC glutathione in almost all cases, and greatly improved abnormal platelet counts, suggesting a significant decrease in inflammation
The generation of transgenic mice deficient in just one antioxidant enzyme has been a major approach to get further insight on the individual role of each peroxidase (Ho et al., The peroxidases catalyze redox reactions involving peroxides cleavage (Mhamdi et al., 2012
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